BioMate AI
About BioMate

New medicines for the immune system

BioMate is building a new generation of medicines for immune-mediated disease — autoimmune, chronic infection, and immuno-oncology. We identify targets from human biology and design cyclic-peptide medicines, on an AI platform of our own: self-hosted models, a closed loop that gets stronger with every experiment, and honest, private validation. The same platform is open to any team doing hard science.

How it fits together

The platform and the program it powers

The biomedical research platform

Connecting tools is only the start

Plenty of products wire existing tools together. BioMate is different in kind: it brings proprietary techniques into one environment — a self-hosted model trained for scientific work, an advanced closed-loop system with a verifiable reward, and reproducible execution across 4,000+ catalog workflows in 36 biomedical domains.

It is the foundation we build on, the one we always use to do what we need — and it is open to any team doing hard science.

Our program on the platform

First the target then the molecule

We run our own drug development on that platform. First we identify the target — the choice that most often decides whether a drug works — from human genetics and patient data. Then we design the molecule: an AI-designed cyclic peptide, optimized in silico against every constraint and proven in the wet lab, round after round.

Our focus is immune-mediated disease — autoimmune, chronic infection, and immuno-oncology. Pre-clinical today.

Our story

Built for the organizations doing the hardest science

BioMate was founded in late 2025 by a team with deep roots in biomedical informatics and NLP. The founding insight was simple: the bottleneck in computational life science is not capability — it is access. The tools exist. The methods are published. What is missing is a platform that makes them usable by the scientists who need them, without requiring a computational specialist at every step.

We built the platform the way the science demanded: evidence-grounded, auditable, and broad enough to cover the full span of computationally demanding biomedical work — from genomics and structural biology to drug discovery, clinical pharmacology, and regulatory documentation. Where we go deepest is immune-mediated disorders: nominating and de-risking targets, designing peptide and macrocycle candidates, and closing the design–make–test loop with wet-lab feedback.

Every result on BioMate is defensible — by design, not by documentation.

Today BioMate is in production with pilot teams across pharma, biotech, CROs, and academic medical centers — 4,000+ indexed workflows, 36 domains, and a quality framework that regulatory reviewers and journal editors can inspect at the parameter level.

At a glance

BioMate AI — key facts

Founded Late 2025
Headquarters Houston, Texas — Texas Medical Center
Platform AI platform integrating our own model, an advanced closed-loop system, and 4,000+ catalog workflows across 36 biomedical domains
Focus program (on the platform) Our own drug development: cyclic-peptide therapeutics for immune-mediated disease (target ID · molecular design · closed-loop). Pre-clinical.
Key integrated tools GATK, DeepVariant, STAR, salmon, Seurat, AlphaFold 2/3, CryoSPARC, AutoDock Vina, GROMACS, DESeq2, MaxQuant, QIIME 2
Pricing Free — no card required; Pro $49/mo; Team $199/mo; Enterprise — contact sales
Compliance HIPAA-compliant; BAA available; private VPC deployment option
Data policy Your data is never used to train shared AI models; tenant-isolated workspace
What we believe

Principles that shape every decision

Not aspirational statements. The constraints we apply when deciding what to build, what to charge, and what to refuse.

Scientific coverage

36 domains · 4,000+ workflows · one interface

BioMate spans the full breadth of modern life science research — from raw sequencing data to IND-ready documents. Each domain draws on the community's gold-standard open-source tools, accessible through a plain-English request.

Genomics & Variant Calling
GATK HaplotypeCaller, DeepVariant, nf-core/sarek — germline and somatic variant calling, CNV, SV detection.
Transcriptomics
STAR, Salmon, DESeq2, edgeR, clusterProfiler — bulk RNA-seq from raw reads to differential expression and pathway enrichment.
Single-Cell Analysis
Seurat, Scanpy, SingleR, Cell Ranger — clustering, cell-type annotation, trajectory inference, and condition-level comparisons.
Structural Biology
AlphaFold 2 & 3, ESMFold, RoseTTAFold, AutoDock Vina, GROMACS — structure prediction, docking, and molecular dynamics.
Cryo-EM
CryoSPARC, RELION — GPU-accelerated single-particle analysis, 2D classification, 3D refinement, and resolution estimation.
Drug Discovery & ADMET
Virtual screening, ADMET profiling, PBPK simulation, hERG liability, IND document assembly — full preclinical pipeline.
Epigenomics
minfi, DMRcate, bismark — bisulfite sequencing, differentially methylated region calling, and chromatin accessibility analysis.
Proteomics & Metabolomics
MaxQuant, MSstats, XCMS — label-free quantification, PTM analysis, and metabolic network modeling.
Metagenomics & Microbiome
QIIME 2, Kraken2, MetaPhlAn — amplicon and shotgun metagenomics, taxonomy profiling, and diversity analysis.
Bioconductor & R Methods
1,818 Bioconductor packages available through plain-English requests — the full peer-reviewed R ecosystem, no coding required.
Community Databases
gnomAD, ClinVar, GTEx, Reactome, KEGG, STRING, OpenTargets, UniProt, PubMed — queryable directly within workflows.
And 25 more domains…
Immunology, synthetic biology, imaging, pharmacology, rare disease, cancer biology, and more.
See full coverage →

Start your free pilot today

No card. No procurement. Bring your hardest target‑validation question; BioMate handles the rest.